Microbial transformation of the diterpene mulin-11,13-dien-20-oic acid by Mucor plumbeus

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Microbial transformation of the diterpene mulin-11,13-dien-20-oic acid by Mucor plumbeus

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Microbial transformation of the diterpene mulin-11,13-dien-20-oic acid by Mucor plumbeus

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Title: Microbial transformation of the diterpene mulin-11,13-dien-20-oic acid by Mucor plumbeus
Author: Areche, Carlos; Loyola, Luis Alberto; Bórquez, Jorge; Rovirosa, Juana; San Martín, Aurelio
Abstract: Two new mulinane-type derivatives: 16-hydroxy mulin-11,13-dien-20-oic (2) acid and 7 alpha,16-dihydroxy mulin-11,13-dien-20-oic (3) acid were obtained by microbial transformation of mulin-11,13-dien-20-oic acid (1), along with tyrosol (4) using liquid cultures of Mucor plumbeus. The latter compound has not been previously identified in the genus Mucor. Structural elucidation of these metabolites was achieved using 1D- and 2D-NMR spectroscopy.
URI: http://www.captura.uchile.cl/handle/2250/6639
Date: 2008-08
dc.identifier.citation: MAGNETIC RESONANCE IN CHEMISTRY Volume: 46 Issue: 8 Pages: 765-768 Published: AUG 2008


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