Active metabolites from Dunalia spinosa resinous exudates

Abstract

Dunalia sphiosa, a plant used in folk medicine for toothaches, breathing problems and cleansing wounds. was found active as antimicrobial and antioxidant. A new (E)-aurone rutinoside (dunaurone) has been isolated from the aerial parts of the plant, and its structure was determined by spectroscopic means. Lupeol, beta-sitosterol, scopoletin, quercetin and withaferin A were also found. All the extracts exhibited strong antimicrobial activity while dunaurone showed only weak antimicrobial inhibition against Klebsiella pneumoniae: in addition it presented a significant free radical scavenging activity.