| Title: | Effects of simple and angular chromones on tumor cell respiration |
| Author: | Araya Maturana, R.; Heredia Moya, Jorge; Donoso Tauda, Oscar; Vera Castillo, Mario Francisco; Toledo Hernández, Jorge; Pavani, Mario; Pessoa, H.; Weiss López, B. E.; Ferreira, J. |
| Abstract: | A set of structurally related compounds incorporating a chromone moiety as an essential component of their structures were tested against the TA3 mouse carcinoma cell line and its multidrug-resistant variant TA3-MTX-R. A tentative structure-activity relationship was found for this family of substances, suggesting that a Michael addition at C-1 is involved in the mechanism that provokes the activities. |
| URI: | http://www.captura.uchile.cl/handle/2250/5194 |
| Date: | 2008 |
| dc.identifier.citation: | NATURAL PRODUCT COMMUNICATIONS 3(4):519-524 |
| Files | Size | Format | View |
|---|---|---|---|
| Chromones ARAYA, 2008.pdf | 1.198Mb |
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