Synthesis, structure and antifungal properties of Co(II)-sulfathiazolate complexes

Abstract

he reaction between sulfathiazole and cobalt(II) leads to a pink solid, [Co-II(ST)(2)(H2O)(4)] (1), which, after 7-10 days in the mother solution, transforms into red crystals of [Co-II(ST)(2)(H2O)(3)](n) (2) (ST = sulfathiazolate). The Co(II) ion exhibits an octahedral environment in both compounds. Differences between them were noted in the IR spectra in the region corresponding to signals of the amine group. Antifungal properties of (1) were evaluated, showing activity against both Aspergillus fumigatus (the same as the ligand) and Aspergillus flavus (better than the ligand).