Inhibitory Effect of Boldine on Fish Oil Oxidation

Abstract

The 8ntioxidative effect of boldine, an alkaloid extracted (rum Peumus boldus Mol. (boldo), was assayed on the spontaneous and on the metal·induced oxidation of fish oil. The inhibitory effect of boldine was compared to those of di-a tocopherol, the flavonoid quercetin and the synthetie antioxidants butylated hydroxytoluene and butylated hydroxyanisole. Boldine, in all assays, showed a good antioxidative effect, which was comparable to that of quereetin and even better than that of dl·a tocopherol and the synthetie antioxidants. Additive effects wcre observed when mixtures of boldine and quercetin or di-a tocop~erol were assayed. The present study supports the . potentIal use of boldine as a novel natural antioxidant for fish oil.