PRELlMINARY VOLTAMMETRIC DATA FOR THE OXIDATION OF 4-METHYLAMINOPHENETHYLAMINE DERIVATIVES IN BUFFER AND IN APROTIC SOLVENTS

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PRELlMINARY VOLTAMMETRIC DATA FOR THE OXIDATION OF 4-METHYLAMINOPHENETHYLAMINE DERIVATIVES IN BUFFER AND IN APROTIC SOLVENTS

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PRELlMINARY VOLTAMMETRIC DATA FOR THE OXIDATION OF 4-METHYLAMINOPHENETHYLAMINE DERIVATIVES IN BUFFER AND IN APROTIC SOLVENTS

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Título: PRELlMINARY VOLTAMMETRIC DATA FOR THE OXIDATION OF 4-METHYLAMINOPHENETHYLAMINE DERIVATIVES IN BUFFER AND IN APROTIC SOLVENTS
Autor: Rojas, Evelyn; Norambuena, Ester; Olea Azar, Claudio; Reyes Parada, Miguel; Cassels, Bruce K.
Resumen: The electrochemistry 01 a series 01 monoamine oxidase-inhibitory 4-Nmethyl and N,N-dimethylaminophenethylamines was studied using cyclic voltammetry. Electron transler was irreversible both in aqueous buffer.(pH = 7.4) and in aprotic solvents. The peak potentials in buffer solution Hebetween 0.59 and 0.63 V, and increase only slightly upon addition 01 up to 20% (vlv) acetonitrile. These potentials are low enough lor these phenethylamine derivatives to be detected electrochemically under standard conditions used lor HPLC analysis 01 catecholamines, serotonin, and their metabolites.
URI: http://www.captura.uchile.cl/handle/2250/17027
Fecha: 1993-10-15
Cita del item: Bol. Soc. Chil. Quim., Vol. 38, pp. 335-339, 1993.


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