SYNTHESIS OF 2-ARYL-l,3-PROPANEDIAMlNES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE

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SYNTHESIS OF 2-ARYL-l,3-PROPANEDIAMlNES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE

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SYNTHESIS OF 2-ARYL-l,3-PROPANEDIAMlNES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE

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Title: SYNTHESIS OF 2-ARYL-l,3-PROPANEDIAMlNES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE
Author: Iturriaga Vásquez, Patricio; Lühr-Sierra, Susan; Caroli Rezende, Marcos; Cassels, Bruce K.
Abstract: A simple synthetic route for the preparation of 2-phenyl-I,3-propanediamines, based on a Knoevenagel-Michael double .:ondensation followed by reduction, was developed using nitromethane as reagent and solvent, and sodium bicarbonate as base in ¡he first step, followed by catalytic hydrogenation over Adams catalyst.
URI: http://www.captura.uchile.cl/handle/2250/16897
Date: 2006
dc.identifier.citation: J. Chil. Chem. Soc ., Vol. 51, Nº 1, 2006.


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