Animal models of psychopathology: Historical models and the pavlovian contribution

Abstract

Research using non-human animals as experimental subjects to understand human behavior have been based on the Darwinian notion of continuity between species. In this framework, we find analogous models to understand human biology and behavior in nonhuman species. In the scientific study of psychology, animal models have proven to be an effective tool for understanding both normal and abnormal human behaviors. In the present review, we discuss how animal models have been used in investigating psychopathology. After reviewing three historical animal models of specific psychopathologies, we discuss how phenomena discovered while studying Pavlovian conditioning have contributed to our understanding of the etiology and maintenance of human psychopathology, how the Pavlovian tradition has contributed to the development of better ways to treat these behavioral disorders, and more generally, how Pavlovian phenomena are implicated in almost all interactions between an organism and its environment.