Phytochemical and biological study of radal Lomatia hirsuta (Proteaceae)

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Phytochemical and biological study of radal Lomatia hirsuta (Proteaceae)

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Phytochemical and biological study of radal Lomatia hirsuta (Proteaceae)

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Título: Phytochemical and biological study of radal Lomatia hirsuta (Proteaceae)
Autor: Erazo, Silvia; García, R.; Backhouse Erazo, Nadine; Lemus, Igor; Delporte Vergara, Carla; Andrade, C.
Resumen: The anti-inflammatory property of Lomatia hirsuta (Lam.) Diels ex Macbr. (Proteaceae), leaves (radal), a plant used in Chilean traditional medicine for bronchial troubles and asthma, was evaluated. The biological assays showed infusion of L. hirsuta leaves inhibits the inflammation induced by lambda-carrageenan corresponding to a 29.2% anti-inflammatory effect, and to 53.5% of the maximum effect observed with sodium naproxen (4 mg/kg) in the same experimental conditions. The coumarins, umbelliferone and scopoletin, were the major compounds isolated, along with quercetine, rhamnetin and iso-rhamnetin, with minor quantities or quercitrine and no presence of toxic naphthoquinone derivates. These results supported the folk use of L. hirsuta. (C)
URI: http://www.captura.uchile.cl/handle/2250/12598
Fecha: 1997-07
Cita del item: JOURNAL OF ETHNOPHARMACOLOGY 57 (2): 81-83


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