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Title:
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Studies on quinones. Part 36. Synthesis and trypanocidal activity of 2-alkoxycarbonylbenzo[b]thiophene-4,7-quinones |
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Author:
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Pessoa, D.; Valderrama Guerrero, Jaime Adolfo; Olmos, María G.; Espinoza, Omar; Pessoa, H.; Rojas de Arias, Antonieta; Nakayama, Héctor; Torres, Susana; Miret, Jorge
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Abstract:
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A series of 2-alkoxycarbonylbenzo[b]thiophene-4,7-quinones (11-15), prepared from the corresponding acid 5, were tested in vitro against trypomastigote form of Trypanosome cruzi. The influence of the lypophilia and oxidant capacity upon the trypanocidal activity of these members is discussed. |
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URI:
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http://www.captura.uchile.cl/handle/2250/10788
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Date:
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2002 |
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dc.identifier.citation:
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HETEROCYCLIC COMMUNICATIONS 8(2): 135-140 |