Browsing by Subject "SYNAPTOSOMES"

DSpace/Manakin Repository

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C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists

Abin Carriquiry, Juan Andrés;Voutilainen, Merja H.;Barik, Jacques;Cassels, Bruce K.;Iturriaga Vásquez, Patricio;Bermúdez, Isabel;Durand, Claudia;Dajas, Federico;Wonnacott, Susan (2006)

Neuronal nicotinic acetylcholine receptors subserve predominantly modulatory roles in the brain, making them attractive therapeutic targets. Natural products provide key leads in the quest for nicotinic recepto....
Effect of protein-modifying reagents on ecto-apyrase from rat brain

Wink, M. R.;Buffon, A.;Bonan, C. D.;Valenzuela, M. A.;Sarkis, J. J. K.;Battastini, A. M. O. (2000-01)

We have tested several chemical modifiers to investigate which amino acid residues, present in the primary structure of the ecto-apyrase, could be involved in catalysis. Synaptosomes from cerebral cortex of rat....
Sodium-dependent action potentials induced by brevetoxin-3 trigger both IP3 increase and intracellular Ca2+ release in rat skeletal myotubes

Liberona, José Luis;Cárdenas, J. César;Reyes, Roberto;Hidalgo, Jorge;Molgó, Jordi;Jaimovich P., Enrique (2008-09)

Brevetoxin-3 (PbTx-3), described to increase the open probability of voltage-dependent sodium channels, caused trains of action potentials and fast oscillatory changes in fluorescence intensity of fluo-3-loaded....

Now showing items 1-3 of 3