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Depolarization-induced slow Ca2+ transients stimulate transcription of IL-6 gene in skeletal muscle cells

Juretic, Nevenka;García Huidobro, Paola;Iturrieta, Juan Antonio;Jaimovich P., Enrique;Riveros, Nora (2006-05)

Contracting skeletal muscle produces and releases interleukin-6 (IL-6) in high amounts. Nevertheless, the mechanisms underlying IL-6 expression are not understood. Because inositol-1,4,5-trisphosphate (IP3)-med....
NF-kappa B activation by depolarization of skeletal muscle cells depends on ryanodine and IP3 receptor-mediated calcium signals

Valdés, Juan Antonio;Hidalgo, Jorge;Galaz, José Luis;Puentes, Natalia;Silva, Mónica;Jaimovich P., Enrique;Carrasco, María Angélica (2007)

Depolarization of skeletal muscle cells by either high external K+ or repetitive extracellular field potential pulses induces calcium release from internal stores. The two components of this release are mediate....
Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation

Cárdenas, César;Liberona, José Luis;Molgó, Jordi;Colasante, Cesare;Mignery, Gregory;Jaimovich P., Enrique (2005-07-15)

Several lines of evidence indicate that increases in nuclear Ca2+ have specific biological effects that differ from those of cytosolic Ca2+, suggesting that they occur independently. The mechanisms involved in ....
Possible link of different slow calcium signals generated by membrane potential and hormones to differential gene expression in cultured muscle cells

Jaimovich P., Enrique;Espinosa, Alejandra (2004)

The study of fluorescent calcium signals from cultured rat myotubes has provided interesting results in the past few years. Both K+ depolarization and tetanic electrical stimulation were shown to produce slow C....
Single-channel recording of inositol trisphosphate receptor in the isolated nucleus of a muscle cell line

Kusnier, Carlos;Cárdenas, César;Hidalgo, Jorge;Jaimovich P., Enrique (2006)

Nuclear calcium appears to have an important role in the regulation of gene expression in many cells, but the mechanisms involved in controlling nuclear Ca2+ signaling are controversial and still poorly underst....

Now showing items 1-5 of 5

Browsing by Subject "MYOTUBES"

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